Buffalo Nickels, also known as Indian Head Nickels, were minted by the United States from 1913 to 1938. The 1921 Buffalo Nickel, particularly those struck at the San Francisco Mint, is notable for its rarity and demand among collectors. It features a depiction of a Native American on the obverse and an American bison on the reverse, symbolizing the country's heritage. The 1921-S Buffalo Nickel is sought after for its lower mintage and condition sensitivity, making it an important issue in the series for numismatists.

Item Denomination Series Year Mint
1921-S 5c 5c Buffalo Nickels 1921 San Francisco