The 50 Statehood Quarters program, initiated by the United States Mint in 1999, aimed to celebrate each of the 50 states by issuing a quarter featuring unique designs representative of each state. The quarters were released in the order that the states ratified the Constitution. The 2006 San Francisco mint-produced quarters, part of the series, typically feature higher quality silver or clad compositions and are sought after by collectors for their design and limited mintage, especially in uncirculated or proof conditions. These quarters often carry particular value depending on their condition and demand within the numismatic community.

Item Denomination Series Year Mint
2006-S 25c Nebraska Clad DCAM 25c 50 Statehood Quarters 2006 San Francisco